Cleveland Guardians starting pitcher Joey Cantillo throws during the first inning of a baseball game against the St. Louis Cardinals Tuesday, April 14, 2026, in St. Louis. (AP Photo/Jeff Roberson)

ST. LOUIS — Cardinals rookie JJ Wetherholt homered twice, second baseman Juan Brito allowed Masyn Winn’s potential game-ending grounder to bounce into right field and St. Louis stopped a three-game losing streak when it rallied to beat the Cleveland Guardians 6-5 in 10 innings on Tuesday.

Wetherholt had his first multi-homer game, going deep for the first time since homering in his debut on opening day. His solo homer off Joey Cantillo tied the score 2-2 in the third and his two-run drive against Erik Sabrowski cut the Cardinals’ deficit to 5-4 in the eighth.

With two outs in the ninth, Winn reached when his two-hopper hit off Brito’s wrist for just the sixth error by Cleveland this season. Winn advanced on Cade Smith’s wild pitch and scored on Yohel Pozo’s opposite-field double that bounced to the right-center field wall.

Riley O’Brien (2-0) pitched a perfect 10th, stranding Chase DeLauter at third when Brito grounded out.

Thomas Saggese advanced to third in the bottom half on a wild pitch by Tim Herrin (0-1) and scored with a headfirst slide, just beating the throw from right fielder Angel Martinez on Nathan Church’s sacrifice fly.

Ivan Herrera hit his first home run this season for St. Louis, which improved to 4-0 in extra innings with its seventh comeback win.

Jose Ramirez hit a first-inning homer off Michael McGreevy and with 288 moved past Bernie Williams and Bobby Bonilla into sole possession of 11th place among switch-hitters.

Cleveland opened a 5-2 lead in the eighth on George Valera’s tiebreaking double and Martinez’s two-run double.

Up next

Cleveland RHP Slade Cecconi (0-2, 5.74 ERA) goes against St. Louis RHP Dustin May (1-2, 9.45) today.